Selected Publications 2008/2009

A.  Original Communications in Peer-Reviewed Journals 2008-2009
  • Wang, Z.V., Deng, Y., Wang, Q.A., Sun, K. and P.E. Scherer. Identification and Characterization of a Promoter Cassette Conferring Adipocyte-Specific Gene Expression. Endocrinology, in press.
  • Nawrocki, A.R., Hofmann, S.M., Teupser, D., Basford, J.E., Durand, J.L., Jelicks, L.A., Woo, C.W., Kuriakose, G., Factor, S.M., Tanowitz, H.B., Hui, D.Y., Tabas, I. and P. E. Scherer. Lack of Association between Adiponectin Levels and Atherosclerosis in Mice. Arterioscler Thromb Vasc Bio., in press.
  • Bose, M., Texeira, J., Olivan, B., Bawa, B., Arias, S., Machineni, S., Pi-Sunyer, F.X., Scherer, P.E. and and B. Laferrere. 2010. Weight loss and incretin responsiveness improve glucose control independently after gastric bypass surgery. Journal of Diabetes, 2: 47–55.
  • Rajpathak SN, Wang T, Wassertheil-Smoller S, Strickler HD, Kaplan RC, McGinn AP, Wildman RP,Rosenbaum D, Rohan TE, Scherer PE, Cushman M, Ho GY. Hepatocyte Growth Factor and the Risk of Ischemic Stroke Developing Among Postmenopausal Women. Results From the Women's Health Initiative. Stroke,in press.
  • Wernstedt Asterholm, I. and P. E. Scherer. Enhanced Metabolic Flexibility Associated with Elevated Adiponectin Levels. Am J Pathol, in press.
  • Vernochet, C., Davis, K.E., P. E. Scherer, and Farmer, S.R. Mechanisms Regulating Repression of Haptoglobin Production by Peroxisome Proliferator-Activated Recepter γ Ligans in Adipocytes. Endocrinology, in press.
  • Khan, T., Hamilton, M.P, Mundy, D.I., Chua, S.C. and P. E. Scherer. 2009. Impact of Simvastatin on Adipose Tissue: Pleiotropic Effects in vivo. Endocrinology, 150(12):5262-72.
  • Halberg, N., Schraw, T.D., Wang, Z.V., Kim, J.Y., Yi, J., Hamilton, M.P., Luby-Phelp, K. and P. E. Scherer. 2009. Systemic Fate of the Adipocyte-Derived Factor Adiponectin. Diabetes, 58(9):1961-70.
  • Halberg, N., Khan, T., Trujillo, M.E., Wernstedt-Asterholm, I., Attie, A.D., Sherwani, S., Wang, Z.V., Landskroner-Eiger, S.,  Dineen, S., Magalang, U.J., Brekken, R.A. and P. E. Scherer. 2009. HIF 1 alpha Induces Fibrosis and Insulin Resistance in White Adipose Tissue. Mol Cell Biol, 29(16):4467-83.
  • Rieck, S., White, P., Schug, J., Fox, A.J., Smirnova, O., Gao N., Gupta, R.K., Wang, Z.V., Scherer, P.E., Keller, M.P., Attie, A.D. and K.H. Kaestner. 2009. The transcriptional response of the islet to pregnancy in mice. Mol Endocrinol., 23(10):1702-12.
  • Vernochet, C.,  Peres, S.B., Davis, K.E., McDonald, M.E., Qiang, L., Wang,  H., Scherer, P.E. and S. R. Farmer. 2009. C/EBPα and the corepressors CtBP1/2 regulate repression of select visceral white adipose genes during the induction of the brown phenotype in white adipocytes by PPARγ agonists. Mol Cell Biol, 29(17):4714-28.
  • Landskroner-Eiger, S., Qian, B., Muise, E.S, Nawrocki, A.R., Berger, J.P., Fine, E.J., Koba, W., Deng, Y., Pollard, J.W. and P.E. Scherer. 2009. Proangiogenic Contribution of Adiponectin toward Mammary Tumor Growth In vivo.Clin Canc Res, 15(10):3265-76.
  • Khan, T., Muise, E.S., Iyengar, P, Wang, Z.V., Chandalia, M., Abate, N., Zhang, B.B. Bonaldo, P., Chua, S. and P. E. Scherer. 2008. Metabolic Dysregulation and Adipose Tissue Fibrosis: The Role of Collagen VI.Mol Cell Biol, 29(6):1575-91.
  • Wang, Z.V., Mu, J., Schraw, T.D.,  Gautron, L., Elmquist, J.K., Zhang, B.B., Brownlee, M. and P.E. Scherer. 2008. PANIC–ATTAC, a mouse model for inducible and reversible β cell ablation.Diabetes, 57(8):2137-48.
  • Nagajyothi, F., Desruisseaux, M.S., Thiruvur, N., Weiss, L.M., Braunstein, V.L., Albanese, C., Teixeira, M.M., de Almeida, C.J., Lisanti, M.P., P.E. Scherer and H.B. Tanowitz. 2008. Trypanosoma cruzi Infection of Cultured Adipocytes Results in an Inflammatory Phenotype.Obesity, 16(9):1992-7.
  • Schraw, T., Wang, Z.V., Halberg, N., Hawkins, M. and P.E. Scherer. 2008. Plasma adiponectin complexes have distinct biochemical characteristics.Endocrinology, 149(5):2270-82. 
  • Dallaire, P., Bellmann, K., Laplante, M., Gélinas, S., Centeno-Baez, C., Penfornis, P., Peyot, M.L., Latour, M.G., Lamontagne, J., Trujillo, M.E., Scherer, P.E., Prentki, M., Deshaies, Y. and A. Marette. 2008. Obese mice lacking iNOS are sensitized to the metabolic actions of PPARg agonism. Diabetes, 57(8):1999-2011. 
  • Atzmon, G., Pollin, T.I., Crandall, J., Tanner, K., Schechter, C.B., Scherer, P.E., Rincon, M., Siegel, G., Katz, M., Lipton, R.B., Shuldiner, A.R. and N. Barzilai. 2008. Adiponectin levels and genotype: a potential regulator of life span in humans. J Gerontol A Biol Sci Med Sci., 63(5):447-53. 
  • Sommer, G., Weise, S., Kralisch, S., Scherer, P.E., Loessner, U., Blueher, M., Stumvoll, M. and M. Fasshauer. 2008. The adipokine SAA3 is induced by interleukin-1b in mouse adipocytes. J Cell Biochem, 104(6):2241-7.
  • Wildman, R.P., Mancuso, P., Wang, C., Kim, M., Scherer, P.E. and M.R. Sowers. 2008. Adipocytokine and ghrelin levels in relation to cardiovascular disease risk factors in women at midlife: longitudinal associations. Int J Obes (Lond), 32(5):740-8.


B. Reviews, Commentaries, and Methods, 2008-2009

  • Scherer, P.E. and R. Unger. Gluttony, Sloth and the Metabolic Syndrome: A Roadmap to Lipotoxicity Trends in Endocrinology & Metabolism, in press.

  • Unger, R.H., Clark, G.O., P. E. Scherer, and Orci, L. Lipid Homeostasis, lipotoxicity, and the Metabolic Syndrome. Biochim Biophys Acta, in press.
  • Rutkowski, J.M., Davis, K.E. and P. E. Scherer. 2009. Mechanisms of Obesity and Related Pathologies: The Macro- and Microcirculation of Adipose Tissue. FEBS J.,276(20):5738-46.
  • Kusminski, C.M. and P.E. Scherer. 2009. The Road from Discovery to Clinic: Adiponectin as a Biomarker of Metabolic Status. Clin Pharmacol Ther., 86(6):592-5.
  • Kusminski, C.M., Shetty, S., Orci, L., Unger, R. and P.E. Scherer. 2009. Diabetes and Apoptosis: Lipotoxicity. Apoptosis, 14(12):1484-95.
  • Nagajyothi, F., Desruisseaux, M.S., Jelicks, L.A., Machado, F.S., Chua, S., Scherer, P.E. and H.B. Tanowitz. 2009. Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome. Interdiscip Perspect Infect Dis. in press.
  • Shetty, S., Kusminski, C.M. and P. E. Scherer. 2009. Adiponectin in Health & Disease: Evaluation of adiponectin targeted drug development strategies. Trends Pharmacol Sci., 30(5):234-9.
  • Holland, W.L. and P. E. Scherer. 2009. PAQ receptors: a counteracting force to ceramides? Mol. Pharmacology, 75(4):740-3.
  • Nagajyothi, F., Desruisseaux, M.S., Weiss, L.M., Chua, S., Albanese, C., Machado, F.S., Esper, L., Lisanti, M.P., Teixeira, M.M., Scherer P.E. and H.B. Tanowitz. 2009. Chagas disease, adipose tissue and the metabolic syndrome. Mem Inst Oswaldo Cruz. 2009 Jul;104(4):219-25.
  • Attie, A.D. and P.E. Scherer. 2008. Adipocyte metabolism and obesity. J Lipid Res. 50 Suppl: S395-9.
  • Davis, K. E and P.E. Scherer. 2008. Adiponectin – no longer the lone soul in the fight against insulin resistance? Commentary, Biochem. J., 416(2):e7-9.
  • Wang, Z.V. and P.E. Scherer. 2008. DsbA-L is a versatile player in adiponectin secretion. Commentary, Proc. Natl. Acad. Sci., 105(47) 18077–18078.
  • Halberg, N., Wernstedt Asterholm, I. and P.E. Scherer. 2008. The Adipocyte as an Endocrine Cell. Endocrinology and Metabolism Clinics of North America, 37(3):753-768.
  • Wang, Z.V. and P.E. Scherer. 2008. Adiponectin, Cadiovascular Function and Hypertenstion. Hypertension, 51(1):8-14.